Callophycoic acids A-H (1-8) and callophycols A and B (9 and 10) were isolated from extracts of the Fijian red alga Callophycus serratus, and identified by NMR, X-ray, and mass spectral analyses. These natural products represent four novel carbon skeletons, providing the first examples of diterpene-benzoic acids and diterpene-phenols in macroalgae. Compounds 1-10 exhibited antibacterial, antimalarial, and anticancer activity, although they are less bioactive than diterpene-benzoate macrolides previously isolated from this red alga.
Amy L. Lane, E. Paige Stout, An‐Shen Lin, Jacques Prudhomme, Karine G. Le Roch, Craig R. Fairchild, Scott G. Franzblau, Mark E Hay, William G.L. Aalbersberg, Julia Kubanek
Amy L. Lane, Anne C. Prusak, Mark E Hay, Terry W. Snell, R.A. Giese, Kenneth I. Hardcastle, C.R. Fairchild, William G.L. Aalbersberg, Carmen Raventós-Suárez, Julia Kubanek
Julia Kubanek, Anne C. Prusak, Terry W. Snell, Rachel Giese, Kenneth I. Hardcastle, Craig R. Fairchild, William G.L. Aalbersberg, Carmen Raventós-Suárez, Mark E Hay
An‐Shen Lin, E. Paige Stout, Jacques Prudhomme, Karine G. Le Roch, Craig R. Fairchild, Scott G. Franzblau, William G.L. Aalbersberg, Mark E Hay, Julia Kubanek
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