Bioactive Bromophycolides R−U from the Fijian Red Alga <i>Callophycus serratus</i>
Article 2010 en
Authors
AL
An‐Shen Lin
ES
E. Paige Stout
JP
Jacques Prudhomme
Abstract
1 min read
Four new bromophycolides, R-U (1-4), were isolated from the Fijian red alga Callophycus serratus and were identified by 1D and 2D NMR and mass spectroscopic analyses. These compounds expand the known structural variety of diterpene-benzoate macrolides and exhibited modest cytotoxicity toward selected human cancer cell lines. Bromophycolide S (2) also showed submicromolar activity against the human malaria parasite Plasmodium falciparum.
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