Synthesis, docking, enzymatic and cellular assays of thieno[3,2-b]pyridine-thioether-1,3-diarylureas as VEGFR2 inhibitors

Maria João R.P. Queiroz; Daniela Peixoto; Ricardo C. Calhelha; Rui M.V. Abreu; Hugo J.C. Froufe; Isabel Cristina Fernandes Rodrigues Ferreira; Raquel Costa; Raquel Soares

Abstract

1 min read

Acknowledgments: To FCT–Portugal for financial support through the PTNMR network. To FCT and COMPETE/QREN/EU for financial support through the research unities PEst-C/QUI/UI686/2011, PEst-OE/AGR/UI0690/2011, PEst-OE/SAU/UI0038/2011, the research project PTDC/QUI-QUI/111060/2009 and the post-Doctoral grant attributed to R.C.C. (SFRH/BPD/68344/2010) also financed by POPH and FSE.

Related publications

Article2012

1-Aryl-3-[ 4-( thieno[3,2-d]pyrimidin-4-yloxy )phenyl]ureas as VEG FR2 inhibitors: synthesis, docking enzymatic and cellular assays

Daniela Peixoto, Ricardo C. Calhelha, Pedro Soares, Rui M.V. Abreu, Hugo J.C. Froufe, Isabel Cristina Fernandes Rodrigues Ferreira, Raquel Costa, Raquel Soares

Article2013

Heteroarylether 1,3-diarylureas in the thieno[3,2-d]pyrimidine series as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays

Maria João R.P. Queiroz, Daniela Peixoto, Pedro Soares, Rui M.V. Abreu, Hugo J.C. Froufe, Ricardo C. Calhelha, Isabel Cristina Fernandes Rodrigues Ferreira, Raquel Costa, Raquel Soares

Article2013

Synthesis, growth inhibitory activity on human tumor cell lines and evaluation of the hepatotoxicity of di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series

Ricardo C. Calhelha, Daniela Peixoto, Pedro Soares, Isabel Cristina Fernandes Rodrigues Ferreira, Rui M.V. Abreu, Maria João R.P. Queiroz

Article2012

1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays

Maria João R.P. Queiroz, Daniela Peixoto, Pedro Soares, Rui M.V. Abreu, Hugo J.C. Froufe, Ricardo C. Calhelha, Isabel Cristina Fernandes Rodrigues Ferreira, Raquel Costa, Raquel Soares

Article2012

Thieno[3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines

Ricardo C. Calhelha, Daniela Peixoto, Pedro Soares, Rui M.V. Abreu, Isabel Cristina Fernandes Rodrigues Ferreira, Maria João R.P. Queiroz

Synthesis, docking, enzymatic and cellular assays of thieno[3,2-b]pyridine-thioether-1,3-diarylureas as VEGFR2 inhibitors

Abstract

Discussion(0)

Related publications

1-Aryl-3-[ 4-( thieno[3,2-d]pyrimidin-4-yloxy )phenyl]ureas as VEG FR2 inhibitors: synthesis, docking enzymatic and cellular assays

Heteroarylether 1,3-diarylureas in the thieno[3,2-d]pyrimidine series as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays

Synthesis, growth inhibitory activity on human tumor cell lines and evaluation of the hepatotoxicity of di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series

1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays

Thieno[3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines