Design, synthesis, and evaluation of “dual-site”-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase

Da Feng; Xiaofang Zuo; Lanlan Jing; Chin‐Ho Chen; Fisayo A. Olotu; Hao Lin; Mahmoud E. S. Soliman; De Clercq Erik; Christophe Pannecouque; Kuo‐Hsiung Lee; Dongwei Kang; Xinyong Liu; Peng Zhan

doi:10.1016/j.ejmech.2020.113063

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Design, synthesis, and evaluation of “dual-site”-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase

Article 2020 en

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Design, synthesis, and evaluation of “dual-site”-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase

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Identification of “dual-site”-binding diarylpyrimidines targeting both NNIBP and the NNRTI adjacent site of the HIV-1 reverse transcriptase

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