2,859 publications from this institution
In drug delivery, surfactants are used to reduce side effects and to increase drug efficiency. The present work aimed to study the interaction of diphenhydramine hydrochloride (anti-allergic drug) with TX-45 (non-ionic surfactant) in the absence and presence of ionic liquid (1-hexyl-3-methylimidazolium chloride). The physicochemical parameters were estimated by the surface tension measurement. Various theoretical models (Clint, Rubingh, Motomura, and Maeda) were applied to determine the attractive behavior between drug and surfactant mixtures at the surface and in bulk. The drug and surfactant mixtures exhibit synergistic behavior in the absence and presence of ionic liquid. Several energetic parameters were also estimated with the assistance of regular solution approximation and pseudo phase separation model that indicate micelle formation and adsorption of surfactant at the surface is thermodynamically advantageous. The morphology of pure and mixture of amphiphiles has been estimated by the Tanford and Israelachvili theories. UV-visible spectroscopy was used to quantify the attractive behavior of the drug with surfactant with the help of a binding constant (<i>K</i>).
In this work, a new fluorescence photoswitching system consisting of fulgide as a photochrome and rhodamine 6G as a fluorophor was designed and studied in methanol, dichloromethane and dioxane. The spectra of both the closed form of fulgide and rhodamine 6G were overlapped. Since the fulgide exhibited non-fluorescence, the emission spectra of blended system were attributed to rhodamine 6G only. The intensity of the fluorescence emission spectra of the rhodamine 6G was modified by the photochromism of fulgide upon irradiation with UV light at different time in methanol, dichloromethane and dioxane. The blended system exhibited quenching in fluorescence emission spectra in different solvents.
Copper oxide doped iron oxide nanocrystals (CuO·Fe<sub>2</sub>O<sub>3</sub>NCs) were prepared using a simple hydrothermal technique at low temperature in an alkaline medium.
Abstract C 18 H 23 NO, triclinic, P 1̄ (no. 2), a = 6.0033(3) Å, b = 11.5667(7) Å, c = 23.5556(12) Å, α = 77.121(5)°, β = 89.635(4)°, γ = 78.852(5)°, V = 1563.27(15) Å 3 , Z = 4, R gt ( F ) = 0.0630, wR ref ( F 2 ) = 0.1733, T = 296(2) K.
The book Carbon Nanotubes - Recent Progress contains a number of recent researches on synthesis, growth, characterization, development, and potential applications on carbon materials especially CNTs in nanoscale. It is a promising novel research from top to bottom that has received a lot of interest in the last few decades. It covers the advanced topics on the physical, chemical, and potential applications of CNTs. Here, the interesting reports on cutting-edge science and technology related to synthesis, morphology, control, hybridization, and prospective applications of CNTs are concluded. This potentially unique work offers various approaches on the R&D implementation of carbon-related materials and their hybrids. Basically, we know that nanotechnology offers the regulating of substances at the nanoscale and nanodimension substances in few nanometers, in which exclusive phenomenon facilitates us to control the novel practical applications with carbon materials or CNTs. Here, in this book, an overview of current CNTs' fundamental and substantial applications and enactment of the research worldwide is presented. The techniques of CNT preparation, types of carbon material utilization, and possible applications related with CNTs or carbon-hybrid material researches were investigated. It is an important booklet for research organizations, governmental research centers, academic libraries, and R&D affianced in recent research and development of carbon nanotubes.
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
The facile hydrothermal method was used to prepare low-dimensional doped Ag<sub>2</sub>O/Sb<sub>2</sub>O<sub>3</sub> nanoparticles (NPs) at low temperature in alkaline medium. The calcined NPs were characterized in detail by FTIR, UV/vis, FESEM, XPS, EDS, and XRD. A thin layer of Ag<sub>2</sub>O/Sb<sub>2</sub>O<sub>3</sub> NPs was deposited onto a glassy carbon electrode (GCE) using Nafion (5% Nafion suspension in ethanol) conducting binder, which formed the working electrode of the selective 3-methoxyphenol electrochemical sensor probe. The proposed chemical sensor exhibits high sensitivity, long-term stability, and enhanced electrochemical responses towards 3-methoxyphenol. Response to 3-methoxyphenol is linear over the concentration range (LDR) of 0.09 nM to 0.09 mM. The analytical parameters of the sensor such as sensitivity, stability, response time, linearity, LDR, robustness, selectivity <i>etc.</i> were evaluated by an electrochemical approach. The sensor probe fabricated with Ag<sub>2</sub>O/Sb<sub>2</sub>O<sub>3</sub> NPs seems to be a promising candidate for effective and reliable electrochemical detection of hazardous and carcinogenic chemicals in the environment and health care fields in large scales.
Objective: The present study aims to find out the presence of potential bioactive compounds in the mangrove plant Avicennia marina (Forssk.) Vierh, through thin-layer chromatography (TLC), observes the antibacterial activity of various solvent extracts of the plant parts against the pathogens Escherichia coli ATCC 25922 and Listeria monocytogenes ATCC 19115. Methods: TLC of the methanol, ethyl acetate, chloroform solvent extracts of stem, root, and leaf of mangrove plant A. marina (Forssk.) Vierh was studied with the mobile phase hexane: ethyl acetate in the ratio of 1;1, 3;7, and 7;3. The spots were identified at ultraviolet 240 nm. Antibacterial activity of the solvent extracts of different plant parts was done against L. monocytogenes ATCC 19115 and E. coli ATCC 25922 by well diffusion method. Results: The thin-layer chromatographic technique revealed the presence of the potential bioactive compound in the A. marina (Forssk.) Vierh. The solvent extracts of different plant parts showed the zone of inhibition for the antibacterial effect ranges between 1 mm and 9 mm. The methanol root extract showed a maximum inhibitory effect against L. monocytogenes ATCC 19115. The methanol stem and leaf extract showed maximum inhibition against E. coli ATCC 25922. Conclusion: The present study emphasizes the importance of exploring the mangrove plant A. marina (Forssk.) Vierh is a potent source of bioactive compounds.
The title compound, 2,6-bis(ethyl-9-ethyl-9H-carbazolylmethylene)cyclohexanone has been synthesized by condensation of 9-ethylcarbazole-3-aldehyde and cyclohexanone in ethanol in the presence of pyridine. The structure of this new compound was confirmed by elemental analysis, IR, 1H NMR, 13C NMR and EI-MS spectral analysis.
The title compound, C(10)H(11)ClN(2)O(2), features an almost planar C(ar)-N(H)-N=C(Cl) unit [torsion angle = 0.8 (1)° whose phenyl substituent is almost coplanar with it [dihedral angle = 2.8 (2)°]; this unit is slightly twisted with respect to the carboxyl -CO(2) fragment [dihedral angle = 10.3 (2)°]. In the crystal, the amino group acts as a hydrogen-bond donor to the carbonyl O atom of an adjacent mol-ecule; the hydrogen bond generates a helical chain that runs along the b axis of the monoclinic unit cell.
