2,859 publications from this institution
The title compound, 1-{[(3,4-dimethylisoxazol-5-yl)imino]methyl}-2-naphthol has been synthesized by condensation of 5-amino-3,4-dimethylisoxazole and 2-hydroxy-1-naphthaledhyde in ethanol. The structure of this new compound was confirmed by elemental analysis, IR, 1H-NMR, 13C-NMR and EI-MS spectral analysis.
A novel multi-metal oxide nanocomposite, Ag<sub>2</sub>O·SrO·CaO, was synthesized by a facile co-precipitation method followed by calcinations. The synthesized nanocomposite was characterized by XRD, FESEM, EDS, TEM, FTIR spectroscopy and photoluminescence (PL) spectroscopy. The composite showed enhanced photocatalytic activity under visible light irradiation and excellent anti-bacterial performance against both Gram-positive and Gram-negative bacteria. Here, the synthesized Ag<sub>2</sub>O·SrO·CaO nanomaterials were deposited on a glassy carbon electrode (GCE) in the form of a thin film to fabricate the desired electrochemical sensor and subjected to <i>I</i>-<i>V</i> analysis of 3-chlorophenol (3-CP) in a phosphate buffer solution (PBS). A calibration curve was plotted from the linear relation of current <i>versus</i> concentration and used to calculate the sensitivity (8.9684 μA μM<sup>-1</sup> cm<sup>-2</sup>), linear dynamic range (LDR, 0.1 nM to 0.01 mM) and lower limit of detection (DL, 97.12 ± 4.86 pM). The analytical parameters of the sensor such as response time, reproducibility and long-term stability in the detection of 3-CP were reliable. Finally, it was used to analyze real samples collected from various environmental sources and found to be acceptable.
A series of 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one-containing Schiff bases were synthesized, characterized and screened for their antibacterial activities. The structures of the synthesized compounds were established by spectroscopic (FT-IR, ¹H-NMR, ¹³C-NMR, MS) and elemental analyses. The anti-bacterial activities (with MIC values) of compounds were evaluated. The anti-bacterial screening results reveal that among the six compounds screened, four compounds showed moderate to good anti-bacterial activity. Among the tested compounds, the most effective compounds against four bacterial strains, viz. Escherichia coli, Staphylococcus aureus, Salmonella typhimurium and Streptococcus pyogenes, are [(2-chlorobenzylidene)amino]-1,5-dimethyl-2-phenyl-1,2-dihydropyrazol-3-one (4) and [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylimino)methyl]benzonitrile (5) with MIC values of 6.25 μg/mL.
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
The mol-ecule of the title compound, C(18)H(13)NO(3), is almost planar, the dihedral angle between the naphthalene and benzene ring systems being 4.04 (6)°. The mol-ecular conformation and packing are stabilized by intra-molecular O-H⋯N and inter-molecular O-H⋯O and C-H⋯O inter-actions.
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
The mol-ecule of the title compound, C(17)H(18)O(3)S, is essentially planar: the phenyl and thio-phene rings form a dihedral angle of 2.79 (10)° and they are inclined to the central propenone unit by 6.20 (15) and 4.78 (15)°, respectively. In the crystal, mol-ecules are connected into dimers via pairs of C-H⋯O inter-actions, generating R(2) (2)(14) motifs. π-π stacking inter-actions between the thio-phene rings also occur, with a centroid-centroid distance of 3.8062 (12) Å.
Generally, our ecosystem is continuously contaminated as a result of anthropogenic activities that form the basis of our comfort in our routine life. Thus, most scientists are engaged in the development of new technologies that can be used in environmental remediation. Herein, highly calcined binary metal oxide (Er2O3@NiO) semiconductor nanocomposite (NC) was synthesized using a classical wet chemical process with the intention to both detect and degrade the toxic chemicals in an aqueous medium using a novel electrochemical current–potential (I–V) approach for the first time. Optical, morphological, and structural properties of the newly synthesized semiconductor NC were also studied in detail using FT-IR, UV/Vis., FESEM-EDS, XPS, BET, EIS, and XRD techniques. Then, a modified glassy carbon electrode (GCE) based on the newly synthesized semiconductor nanocomposite (Er2O3@NiO-NC/Nafion/GCE) as a selective electrochemical sensor was fabricated with the help of 5% ethanolic-Nafion as the conducting polymer binder in order to both detect and electro-hydrolyze toxic chemicals in an aqueous medium. Comparative study showed that this newly developed Er2O3@NiO-NC/Nafion/GCE was found to be very selective against m-tolyl hydrazine (m-Tolyl HDZN) and to have good affinity in the presence of other interfering toxic chemicals. Analytical parameters were also studied in this approach to optimize the newly designed Er2O3@NiO-NC/Nafion/GCE as an efficient and selective m-Tolyl HDZN sensor. Its limit of detection (LOD) at an SNR of 3 was calculated as 0.066 pM over the linear dynamic range (LDR) of our target analyte concentration (0.1 pM–0.1 mM). The limit of quantification (LOQ) and sensitivity were also calculated as 0.22 pM and 14.50 µAµM−1cm−2, respectively. m-Tolyl HDZN is among the toxic chemicals in our ecosystem that have lethal effects in living beings. Therefore, this newly designed electrochemical sensor based on semiconductor nanostructure material offers, for the first time, a cost-effective technique, in addition to long-term stability, that can be used as an alternative for efficiently probing other toxic chemicals in real samples.
Metal organic frameworks (MOFs) are widely used as solid catalysts in the liquid phase under batch mode conditions. Moving towards the development of industrial processes, data of the performance of MOFs under continuous flow operation would be desirable. This feature article describes the state of the art regarding the use of MOFs as catalysts of continuous flow processes, paying special attention to the issue of catalyst stability. The review is organized according to the type of bond that is formed in the reaction from C-C, to C-O to C-N bonds. Examples are presented of MOF catalysts that are stable under continuous flow operation, even for those structures that are not very stable such as Cu3(BTC)2. It can be anticipated that there will be a growth in the percentage of studies carried out under continuous flow with the final goal of implementing a commercial chemical process using MOFs as a catalyst.
In the present study, we report on the interaction between an antidepressant drug, amitriptyline hydrochloride, and nonionic surfactants (t-octylphenoxypolyethoxyethanol (TX-100), polyethoxyglycol t-octylphenyl ether (TX-114)), in aqueous electrolyte solutions, with special attention paid to the possible contribution from the ion–dipole type of interaction, by using a spectroscopic approach. The structural difference in the drug and nonionic surfactants also plays a role in tuning the aggregational behavior of the drug–surfactant mixtures. From the I 1/I 3 versus total surfactant concentration plots, the mixed critical micelle concentration (cmc) of various mixtures was computed. Critical assessments by applying Clint, Rubingh, and Motomura models confirm strong interactions in mixed micelle in the bulk of aqueous electrolytic solution. The various micellar parameters, such as micelle mole fraction (), interaction parameter (βm), micropolarity, and micelle aggregation number (N agg), have been determined for all different ratio mixtures. Micelle aggregation numbers (N agg) indicate that the contribution of nonionic surfactants was always more than that of the drug. Stern–Volmer binding constants (K sv) and dielectric constant of mixed systems have also been evaluated from the ratios of respective peak intensities (I 1/I 3 or I 0/I 1).
The asymmetric unit of the title compound, C(10)H(11)ClN(2)O, contains two mol-ecules. The non-H atoms of each mol-ecule lie approximately on a plane (r.m.s. deviations = 0.062 and 0.110 Å), and the C=N double bond has a Z-configuration in both independent mol-ecules. In the crystal, adjacent mol-ecules are linked by N-H⋯O(carbon-yl) hydrogen bonds, forming chains running along [100].
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
