Use of Cyclohexene Epoxides in the Preparation of Carbocyclic Nucleosides

Sergey N. Mikhailov; N. M. Blaton; Jef Rozenski; Jan Balzarini; De Clercq Erik; Piet Herdewijn

doi:10.1080/07328319608002133

Abstract

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Abstracts A simple route towards 4,4-dihydroxymethyl-cyclohexane nucleosides has been developed. The structure of 4,4-dihydroxymethyl-1-(thymin-1-y1)-cyclohexane was confirmed by X-ray analysis. The synthesized compounds were inactive against all viruses tested.

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