Two-Photon Imaging for the Non-Invasive Assessment of Electric Field Effects on Osteogenic Stem Cell Differentiation

Marie Hronik‐Tupaj; William L. Rice; Mark Cronin‐Golomb; Gordana Vunjak‐Novakovic; David Kaplan; Irene Georgakoudi

doi:10.1364/biomed.2008.bmd54

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Two-Photon Imaging for the Non-Invasive Assessment of Electric Field Effects on Osteogenic Stem Cell Differentiation

Article 2008 en

Abstract

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We present the use of two-photon excited fluorescence and second harmonic generation, to monitor electric field effects on osteogenic differentiation of human mesenchymal stem cells in terms of cellular morphology, biochemical composition and collagen deposition.

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