Bioactive Silicate Nanoplatelets for Osteogenic Differentiation of Human Mesenchymal Stem Cells
Article 2013 en
Authors
AG
Akhilesh K. Gaharwar
SM
Silvia M. Mihăilă
AS
Archana Swami
Abstract
1 min read
Novel silicate nanoplatelets that induce osteogenic differentiation of human mesenchymal stem cells (hMSCs) in the absence of any osteoinductive factor are reported. The presence of the silicate triggers a set of events that follows the temporal pattern of osteogenic differentiation. These findings underscore the potential applications of these silicate nanoplatelets in designing bioactive scaffolds for musculoskeletal tissue engineering.
Akhilesh K. Gaharwar, Silvia M. Mihăilă, Archana Swami, Alpesh Patel, Shilpa Sant, Rui L Reis, Alexandra P. Marques, Manuela E. Gomes, Ali Khademhosseini
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John G. Hardy, Rushi C. Sukhavasi, David Aguilar, Maria K. Villancio‐Wolter, David J. Mouser, Sydney A. Geissler, Lindsey Nguy, Jacqueline K. Chow, David Kaplan, Christine E. Schmidt
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