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doi:10.1038/ni986

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TRAM is specifically involved in the Toll-like receptor 4–mediated MyD88-independent signaling pathway

Abstract

Discussion(0)

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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

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TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway