Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

Katherine A. Fitzgerald; Eva M. Pålsson‐McDermott; Andrew Bowie; Caroline A. Jefferies; Ashley Mansell; Gareth Brady; Elizabeth Brint; Aisling Dunne; Pearl Gray; Mary T. Harte; Diane McMurray; Dirk E. Smith; John E. Sims; Timothy A. Bird; Luke O'neill

doi:10.1038/35092578

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

Nature 413(6851): 78-83

Article 2001 English

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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

Abstract

Discussion(0)

Related publications

Mal (MyD88 adapter-like) is a novel Toll IL-1 receptor (TIR) domain-containing adapter which recruits IRAK-2 during Toll-like receptor-4 signal transduction

Mal and MyD88: adapter proteins involved in signal transduction by Toll-like receptors

Mal and MyD88: adapter proteins involved in signal transduction by Toll-like receptors

MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.

Signal Transduction Pathways Activated by the IL-1 Receptor/Toll-Like Receptor Superfamily