A dideoxythymidine analog, viz. 3'-N, N-dimethyl-2'-3'-dideoxythymidine (3) and its 5'-O-carboxyl ester prodrug derivatives (4-6) have been synthesized as probable antiviral agents. All these compounds have shown low to moderate level of antiviral activities against HIV, HSV 1 & 2, reovirus and many others.
Ivan I. Fedorov, E. M. KAZ'MINA, G. V. Gurskaya, Maxim V. Jasko, Valery E. Zavodnic, Jan Balzarini, De Clercq Erik, Abdesslem Faraj, Jean‐Pierre Sommadossi, Jean‐Louis Imbach, Gilles Gosselin
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