The Topography of Brain Microstructural Damage in Amyotrophic Lateral Sclerosis Assessed Using Diffusion Tensor MR Imaging
Article 2011 en
Authors
EC
Elisa Canu
FA
Federica Agosta
NR
Nilo Riva
Abstract
1 min read
In patients with ALS, DTI detects microstructural changes independent of brain tissue loss. The affected regions included both motor and extramotor areas. The extent of ALS-related DTI abnormalities was greater than that disclosed by the volumetric analysis.
Hans-Peter Müller, Martin R. Turner, Julian Großkreutz, Sharon Abrahams, Peter Bede, Varan Govind, Johannes Prudlo, Albert C. Ludolph, Massimo Filippi, Jan Kassubek
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