The Synthesis and Antiviral Activity of Some New S-Adenosyl-L-homocysteine Derivatives and Their Nucleoside Precursors

Pawel J. Serafinowski; Erwin Dorland; Jan Balzarini; De Clercq Erik

doi:10.1080/15257779508012423

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The Synthesis and Antiviral Activity of Some New S-Adenosyl-L-homocysteine Derivatives and Their Nucleoside Precursors

Article 1995 en

Abstract

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Abstract S-Adenosyl-L-homocysteine (SAH) and some of its analogues are potent inhibitors of transmethylation reactions catalysed by S-adenosyl methionine dependent methyltransferases.1

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