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Article 2003 en
Authors
RM
Rafael Merino-Marbán
ED
Exuperio Díez‐Tejedor
BF
Blanca Fuentes
Abstract
1 min read
Background Oral anticoagulation (OAC) is indicated in the secondary prevention of stroke or transient ischemic attacks (TIA) in patients with atrial fibrillation (AF). OAC is being often withheld due to contraindications or fear of bleeding complications, and antiplatelet agents (AA) are given instead. Methods We analyzed recurrent cerebral and noncerebral ischemic vascular events, major intracerebral and extracerebral bleeding and vascular death in 401 consecutive patients with ischemic stroke or TIA with AF who were discharged with OAC, antiplatelet agents (AA), or heparin. The median follow-up time was 25 (15-38) months. Results Patients with oral anticoagulation at time of discharge were significantly younger and had suffered a major stroke less often than patients who received AA or heparin at discharge. The compliance 1 year after discharge was higher in patients discharged with OAC (81%), than in those on AA (56%; P < 0.001). The majority of patients discharged with heparin were subsequently treated with OAC. Patients with AA at discharge suffered ischemic complications significantly more often during the follow-up than patients with OAC or heparin 8
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