The beneficial characteristics of the dihydro- pyridine calcium blockers, including the absence of negative inotropism and the neutral effect on lipids and insulin sensitivity, have rendered them popular first line agents in managing hypertension.Like other antihypertensives, appropriate cost-benefit analyses of their various actions are required before they are prescribed.However, inappropriate extrapolation from small, highly selected and methodologically flawed statistics should not preclude their use.
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