Role of carbonate electrolytes on interaction of quinolone drug with anionic surfactant at various temperatures: A conductometric study

Abstract The role of different carbonate salts on the interaction of anionic surfactant sodium dodecyl sulfate (SDS) with employed quinolone antibiotic drug (ciprofloxacin hydrochloride [CFH]) was explosively inspected through measuring specific conductivity ( κ ) of the investigated system. The drug, CFH, is an excellent antibiotic for the treatment of different bacterial infections like skin, urinary tract, and respiratory infections. The estimated critical micelle concentrations ( cmc ) of SDS were observed to be dwindled in the attendance of electrolytes and cmc reduction continues with the escalation of the electrolyte's concentration. The magnitudes of cmc for the SDS + CFH mixture were reduced with the elevation of temperature in K 2 CO 3 and CaCO 3 medium while increased with the rise of the temperature in the Na 2 CO 3 medium. The magnitudes of counterion binding to micelles ( β ) were increased with the increase of the concentration of Na 2 CO 3 and K 2 CO 3 up to definite value and then reduced with the increase of successive rise of concentration of both salts at all temperatures while decreased monotonically with the rise of electrolyte concentration in CaCO 3 medium. The values of standard free energy ( ) were achieved to be negative in each case suggesting spontaneous self‐assembly formation. The standard entropy change ( ) along with enthalpy change ( ) was also assessed and discussed elaborately.