Pyridazines are organic compounds in which benzene has nitrogen atoms instead of two carbon atoms. The pyridazine structure is one of the heteroaromatic rings that can be developed for drug design. Pyridazinone analogues are found in the structure of drugs with different activities. This core is of interest to medicinal chemists because of its diverse pharmacological activities. In this review, some of the antibacterial and antifungal, analgesic and anti-inflammatory, anticancer, cardiovascular and anticholinesterase compounds with pyridazinone structure are mentioned.
Abdelhakim Bouyahya, Imane Chamkhi, Naoual El Menyiy, Hamza El Moudden, Hicham Harhar, Zineb Lakhlifi El Idrissi, Aya Khouchlaa, Imane Jouadi, Aicha El Baaboua, Doaue Taha, Abdelaali Balahbib, Asaad Khalid, Ashraf N. Abdalla, Gökhan Zengin, Jesus Simal Gandara, Nasreddine El Omari
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