Neuraminidase alters red blood cells in sepsis

Michaël Piagnerelli; Karim Zouaoui Boudjeltia; Alessandro Rapotec; Thibault Richard; Dany Brohée; Sajida Babar; Vanessa Bouckaert; Anne‐Catherine Simon; Jean-Pierre Toko; Therese Walravens; Jean Louis Vincent; Michel Vanhaeverbeek

doi:10.1097/ccm.0b013e31819cebbe

Abstract

1 min read

In sepsis, desialylation under the influence of increased neuraminidase activity may contribute to the alterations in RBC rheology. Inhibition of neuraminidase may represent a new therapeutic option to ameliorate RBC rheology and perhaps oxygen delivery to the cells.

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