Alterations of red blood cell shape and sialic acid membrane content in septic patients

Michaël Piagnerelli; Karim Zouaoui Boudjeltia; Danny Brohee; P. Piro; Eric Carlier; Jean Louis Vincent; Philippe Lejeune; Michel Vanhaeverbeek

doi:10.1097/01.ccm.0000079608.00875.14

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Alterations of red blood cell shape and sialic acid membrane content in septic patients

Article 2003 en

Abstract

1 min read

RBCs of septic patients are characterized by a more spherical shape, a decreased capacity of sphericity in hypo-osmolar solution, and a reduction in the sialic acid content of the RBC membrane. These modifications in RBC shape and membrane may contribute to the RBC rheologic abnormalities frequently described in sepsis.

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