MODIFIED CYCLOBUTANE CARBONUCLEOSIDES: SYNTHESIS AND EVALUATION OF THEIR ANTIVIRAL ACTIVITY

F. Fernández; Antonio R. Hergueta; Carmen López; De Clercq Erik; Jan Balzarini

doi:10.1081/ncn-100002504

Abstract

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The synthesis of some 9-(2-cyclobutylethyl)guanine derivatives and analogous carbonucleosides from 1S-alpha-pinene is here presented. None of them showed detectable selectivity when assayed in the performed anti-viral tests.

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