Next-generation sequencing has provided information on actionable targets and biomarkers of response in oncology. In hepatocellular carcinoma (HCC), Wnt/CTNNB1 mutations characterize the immune-excluded class (cold tumors) and might represent the biomarkers predicting resistance to immune checkpoint inhibitors. Large-scale validation of these data is needed to customize immunotherapy in advanced HCC.See related article by Harding et al., p. 2116.
Anja Lachenmayer, Clara Alsinet, Radoslav Savić, Laia Cabellos, Sara Toffanin, Yujin Hoshida, Augusto Villanueva, Beatriz Mínguez, Philippa Newell, Hung‐Wen Tsai, Jordi Barretina, Swan N. Thung, Stephen C. Ward, Jordi Bruix, Vincenzo Mazzaferro, Myron Schwartz, Scott L. Friedman, Josep M. Llovet
Anja Lachenmayer, Clara Alsinet, Radoslav Savić, Laia Cabellos, Sara Toffanin, Yujin Hoshida, Augusto Villanueva, Beatriz Mínguez, Philippa Newell, Hung‐Wen Tsai, Jordi Barretina, Swan N. Thung, Stephen C. Ward, Jordi Bruix, Vincenzo Mazzaferro, Myron Schwartz, Scott L. Friedman, Josep M. Llovet
Anja Lachenmayer, Clara Alsinet, Radoslav Savić, Laia Cabellos, Sara Toffanin, Yujin Hoshida, Augusto Villanueva, Beatriz Mínguez, Philippa Newell, Hung‐Wen Tsai, Jordi Barretina, Swan N. Thung, Stephen C. Ward, Jordi Bruix, Vincenzo Mazzaferro, Myron Schwartz, Scott L. Friedman, Josep M. Llovet
Anja Lachenmayer, Clara Alsinet, Radoslav Savić, Laia Cabellos, Sara Toffanin, Yujin Hoshida, Augusto Villanueva, Beatriz Mínguez, Philippa Newell, Hung‐Wen Tsai, Jordi Barretina, Swan N. Thung, Stephen C. Ward, Jordi Bruix, Vincenzo Mazzaferro, Myron Schwartz, Scott L. Friedman, Josep M. Llovet
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