The synthesis of medium-sized rings is a formidable challenge in organic chemistry. Toward this end transition-metal-catalyzed intramolecular cyclopropanation via carbenoids has been applied. The authors report a gold(I)-catalyzed process for the asymmetric synthesis of seven- and eight-membered rings. The present work represents an advancement over existing methods of transition-metal-catalyzed intramolecular cyclopropanation and extends the authors previous work involving the transformations of gold(I) carbenoids.
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