Evolving measurements of radical products — how much do they tell us about inflammation?

It is now widely accepted that reactive oxygen species (ROS) such as superoxide radical (O2 ·-), hydrogen peroxide (H2O2) and hydroxyl radical (•OH) reactive chlorine species (RCS) such as hypochlorous acid (HOCl) and reactive nitrogen species (RNS) such as nitrogen monoxide (nitric oxide, NO>•) and oxoperoxonitrate (peroxynitrite, ONOO-) contribute to considerable tissue injury during chronic inflamation (reviewed in [1]).