This study did not show any statistically significant effect of IVIG on MT MRI quantities. Nevertheless, the markedly different percentage change of the NABT MT ratio histogram peak height over time between patients receiving placebo and treated patients suggests a possible role of IVIG treatment in preventing the loss of "truly" normal brain tissue in SPMS patients.
Šarlota Mesaroš, Maria A. Rocca, Maria Pia Sormani, Paola Valsasina, Clyde Markowitz, Nicola De Stefano, Xavier Montalbán, Frederik Barkhof, Jean‐Philippe Ranjeva, Michael Sailer, Ludwig Kappos, Giancarlo Comi, Massimo Filippi
Marco Rovaris, Elda Judica, Jaume Sastre‐Garriga, Àlex Rovira, Maria Pia Sormani, Béatrice Benedetti, Tijmen Korteweg, Nicola De Stefano, Zhaleh Khaleeli, Xavier Montalbán, Frederik Barkhof, David H. Miller, Chris H. Polman, Alan J. Thompson, Massimo Filippi
Franz Fazekas, Per Soelberg Sørensen, Massimo Filippi, Stefan Ropele, Xia Lin, H. W. Koelmel, Óscar Fernández, Carlo Pozzilli, Paul O’Connor, Monika Maas Enriquez, O. R. Hommes
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