Esmolol Administration to Control Tachycardia in an Ovine Model of Peritonitis

Koji Hosokawa; Fuhong Su; Fabio Silvio Taccone; Emiel Hendrik Post; Adriano José Pereira; Antoine Herpain; Jacques Créteur; Jean Louis Vincent

doi:10.1213/ane.0000000000002196

Abstract

1 min read

In this ovine model of abdominal sepsis, early control of tachycardia by esmolol was associated with a transient increase in stroke volume, followed by earlier hypotension. There were no significant effects of esmolol on cerebral perfusion, metabolism, urine output, or survival.

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