Erlotinib Increases Efficacy of 5-Azacitidine (AZA) by Inhibiting Drug Efflux Via ABC-Transporters

Élodie Lainey; Marie Sébert; Sylvain Thépot; Maximilien Tailler; Lionel Adès; Claude Gardin; Guido Guido Kroemer; Pierre Fenaux; Simone Boehrer

doi:10.1182/blood.v116.21.974.974

Related publications

Article2011

Erlotinib Antagonizes Efflux Via ABC Transporters and Decreases P-Gp Cell Surface Expression by Inhibiting SRC Kinase and mTOR Pathways in Acute Myeloid Leukemia (AML)

Élodie Lainey, Marie Sébert, Cyrielle Bouteloup, Carole Leroy, Sylvain Thépot, Maximilien Tailler, Lionel Adès, Claude Gardin, Guido Guido Kroemer, Pierre Fenaux, Simone Boehrer

Article2010

Erlotinib Inhibits ABC Transporters of AML Progenitors with Stem Cell Features and Increases Chemosensitivity to Current AML Drugs

Marie Sébert, Élodie Lainey, Sylvain Thépot, Maximilien Tailler, Lionel Adès, Claude Gardin, Pierre Fenaux, Guido Guido Kroemer, Simone Boehrer

Article2011

Potentiation of Apoptosis in MDS/AML by Combination of Azacitidine and the EGFR-Tyrosine Kinase Inhibitor (TKI) erlotinib

Élodie Lainey, Marie Sébert, Cyrielle Bouteloup, Carole Leroy, Sylvain Thépot, Maximilien Tailler, Lionel Adès, Claude Gardin, Guido Guido Kroemer, Pierre Fenaux, Simone Boehrer

Article2004

The absence of p53 is critical for the induction of apoptosis by 5-aza-2′-deoxycytidine

María Dolores Nieto, Enrique Samper, Mario F. Fraga, Gonzalo González de Buitrago, Manel Esteller, Manuel Serrano

Preprint2024

Supplementary Figure 5 from ATPase Copper Transporting Beta (ATP7B) Is a Novel Target for Improving the Therapeutic Efficacy of Docetaxel by Disulfiram/Copper in Human Prostate Cancer

Liankun Song, Vyvyan Nguyen, Jun Xie, Shang Jia, Christopher J Chang, Edward Uchio, Xiaolin Zi