Disubstituted pyrimidine-5-carboxamide derivatives as novel HIV-1 NNRTIs: Crystallographic overlay-based molecular design, synthesis, and biological evaluation

Da Feng; Hao Lin; Liyang Jiang; Jiaojiao Dai; Xiaoying Zhang; Zhongxia Zhou; Yanying Sun; Zhao Wang; De Clercq Erik; Christophe Pannecouque; Dongwei Kang; Peng Zhan; Xinyong Liu

doi:10.1016/j.ejmech.2022.114957

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Disubstituted pyrimidine-5-carboxamide derivatives as novel HIV-1 NNRTIs: Crystallographic overlay-based molecular design, synthesis, and biological evaluation

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