Discovery of novel indolylarylsulfones as potent HIV-1 NNRTIs via structure-guided scaffold morphing

Tong Zhao; Qing Meng; Dongwei Kang; Jianbo Ji; De Clercq Erik; Christophe Pannecouque; Xinyong Liu; Peng Zhan

doi:10.1016/j.ejmech.2019.111619

Related publications

Article2016

Discovery of novel piperidine-substituted indolylarylsulfones as potent HIV NNRTIs via structure-guided scaffold morphing and fragment rearrangement

Xiao Li, Ping Gao, Boshi Huang, Zhongxia Zhou, Yu Zhao, Yuan Zheng, Huiqing Liu, Christophe Pannecouque, Dirk Daelemans, De Clercq Erik, Peng Zhan, Xinyong Liu

Article2014

Discovery of novel diarylpyrimidines as potent HIV NNRTIs via a structure-guided core-refining approach

Xiao Li, Wen‐Ming Chen, Ye Tian, Huiqing Liu, Peng Zhan, De Clercq Erik, Christophe Pannecouque, Jan Balzarini, Xinyong Liu

Article2013

Discovery of novel pyridazinylthioacetamides as potent HIV-1 NNRTIs using a structure-based bioisosterism approach

Yuning Song, Peng Zhan, Dongwei Kang, Xiao Li, Ye Tian, Zhenyu Li, Xuwang Chen, Wen‐Ming Chen, Christophe Pannecouque, De Clercq Erik, Xinyong Liu

Article2023

Discovery of novel sulfonamide substituted indolylarylsulfones as potent HIV-1 inhibitors with better safety profiles

Shenghua Gao, Letian Song, Yusen Cheng, Fabao Zhao, Dongwei Kang, Shu Song, Mianling Yang, Bing Ye, Wei Zhao, Ya‐Jie Tang, De Clercq Erik, Christophe Pannecouque, Peng Zhan, Xinyong Liu

Article2016

Arylazolyl(azinyl)thioacetanilides. Part 20: Discovery of novel purinylthioacetanilides derivatives as potent HIV-1 NNRTIs via a structure-based bioisosterism approach

Xueyi Lu, Xiao Li, Jiapei Yang, Boshi Huang, Dongwei Kang, Fabao Zhao, Zhongxia Zhou, De Clercq Erik, Dirk Daelemans, Christophe Pannecouque, Peng Zhan, Xinyong Liu