Differential fluorescent response to amino acids based on metal–organic framework Zn-PBC

A novel metal-organic framework (MOF) Zn-PBC (H₂PBC = pyridine-3,5-bis(phenyl-4-carboxylic acid)) was designed and synthesized <i>via</i> a solvothermal reaction with the H₂PBC ligand, and produced a strong fluorescence. The material exhibited good stability and an ideal luminescent property in water. In addition, it was found that Zn-PBC displayed a different fluorescent response to different types of amino acids, and the mechanism was investigated. This research might give insight to the interaction between MOFs and amino acids, which would provide a strategy to fabricate MOF-based sensors for biomolecules in future.