Characterizing the Solution Properties of Supramolecular Systems by Analytical Ultracentrifugation

A modern version of a classical method of macromolecular and biological chemistry, analytical ultracentrifugation, can be used to study the state of association of supramolecular compounds in solution. In order to familiarize the reader with this technique, the apparatus for which is shown here, we describe application of three different types of ultracentrifuge experiment to a cobalt coordination array dissolved in acetone.