The synthesis of two carbocyclic 7-deazaguanosine oxetanocins structurally modified at the C-3' center and lacking the C-2' hydroxymethylene group is described.Neither of these target compounds showed antiviral activity against a battery of DNA and RNA viruses.
De Clercq Erik, Graciela Andreï, Robert Snoeck, Leen De Bolle, Lieve Naesens, Bart Degrève, Jan Balzarini, Y. Zhang, Dominique Schols, Pieter Leyssen, C. Ying, Johan Neyts
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