ACTIVATION OF CYTOTOXIC LYMPHOCYTES IN PATIENTS WITH SCRUB TYPHUS
American Journal of Tropical Medicine and Hygiene 72(4): 465-467
Article 2005 English
Authors
MF
Maaike de Fost
WC
Wirongrong Chierakul
KP
KRIANGSAK PIMDA
Abstract
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Thai patients with scrub typhus caused by the intracellular pathogen Orientia tsutsugamushi displayed elevated plasma concentrations of granzymes A and B, interferon-gamma (IFN)-gamma-inducible protein 10, and monokine induced by IFN-gamma. These data suggest that activation of cytotoxic lymphocytes is part of the early host response to scrub typhus.
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