24 Stratification for cystic fibrosis (CF) disease severity in adults with CF with homozygous F508del mutations by intestinal organoids

Karin M. de Winter‐de Groot; R. van der Meer; R.E.M. van der Wilt; Johanna F. Dekkers; Margot Geerdink; Sabine Michel; Evelien Kruisselbrink; Annelotte M. Vonk; Gitte Berkers; Robert G.J. Vries; Hans Clevers; E.A. van de Graaf; F.P. Vleggaar; H.G.M. Heijerman; C.K. van der Ent; Jeffrey M. Beekman

doi:10.1016/s1569-1993(16)30264-8

Article2019

Forskolin-induced swelling of intestinal organoids correlates with disease severity in adults with cystic fibrosis and homozygous F508del mutations

Karin M. de Winter – de Groot, Gitte Berkers, Rozemarijn E.P. Marck – van der Wilt, Renske van der Meer, Annelotte M. Vonk, Johanna F. Dekkers, Margot Geerdink, Sabine Michel, Evelien Kruisselbrink, Rob B.M. de Vries, Hans Clevers, Frank P. Vleggaar, Sjoerd G. Elias, Harry Heijerman, Cornelis K. van der Ent, Jeffrey M. Beekman

Article2019

WS04-5 The TOPAZ study, a large-scale study in organoids derived from F508del homozygous cystic fibrosis patients treated with Orkambi

Jasper Mullenders, Marvin Statia, Peter van Mourik, Annelotte M. Vonk, B. Aguilera, R. van der Meer, Harry Heijerman, Hettie M. Janssens, Hans Clevers, J. Beekman, Kors van der Ent, Robert G.J. Vries, Sylvia F. Boj

Article2018

Stratifying infants with cystic fibrosis for disease severity using intestinal organoid swelling as a biomarker of CFTR function

Karin M. de Winter-de Groot, Hettie M. Janssens, Rick T. van Uum, Johanna F. Dekkers, Gitte Berkers, Annelotte M. Vonk, Evelien Kruisselbrink, Hugo Oppelaar, Robert G.J. Vries, Hans Clevers, Roderick H.J. Houwen, Johanna C. Escher, Sjoerd G. Elias, Hugo R de Jonge, Yolanda B. de Rijke, Harm A.W.M. Tiddens, Cornelis K. van der Ent, Jeffrey M. Beekman

Article2014

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation

Daniela De Stefano, Valeria Rachela Villella, Speranza Esposito, Antonella Tosco, Angela Sepe, Fabiola De Gregorio, Laura Salvadori, Rosa Grassia, Carlo Antonio Leone, Giuseppe De Rosa, Maria Chiara Maiuri, Massimo Pettoello‐Mantovani, Stefano Guido, Anna Bossi, Anna Zolin, Andrea Venerando, Lorenzo A. Pinna, Anil Mehta, Gianni Bona, Guido Guido Kroemer, Luigi Maiuri, Valeria Raia

Dataset

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation

Daniela De Stefano, Valeria Rachela Villella, Speranza Esposito, Antonella Tosco, Angela Sepe, Fabiola De Gregorio, Laura Salvadori, Rosa Grassia, Carlo Antonio Leone, Giuseppe De Rosa, Maria Chiara Maiuri, Massimo Pettoello‐Mantovani, Stefano Guido, Anna Bossi, Anna Zolin, Andrea Venerando, Lorenzo A. Pinna, Anil Mehta, Gianni Bona, Guido Guido Kroemer, Luigi Maiuri, Valeria Raia

24 Stratification for cystic fibrosis (CF) disease severity in adults with CF with homozygous F508del mutations by intestinal organoids

Discussion(0)

Related publications

Forskolin-induced swelling of intestinal organoids correlates with disease severity in adults with cystic fibrosis and homozygous F508del mutations

WS04-5 The TOPAZ study, a large-scale study in organoids derived from F508del homozygous cystic fibrosis patients treated with Orkambi

Stratifying infants with cystic fibrosis for disease severity using intestinal organoid swelling as a biomarker of CFTR function

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation

Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation