317 publications from this institution
The three associated genes RPS5, RPS6, and RPS16 were markedly related to degree of T cell infiltration and immune-related activated. We identified their potential biomarkers and therapeutic targets associated with the extent of CD8+ T cell infiltration in GBM.
No abstract is provided for this article.
针对252Cf自发裂变中子源构成的核信息系统，以实际所测随机中子脉冲数据的自相关函数为研究对象，借助仿真实验， 利用Elman神经网络对不同质量核材料进行识别。在实测数据的基础上，通过叠加随机抖动，模拟产生了不同质量核材料的相关函数样本，并将其用于神经网络的训练与测试，实验结果表明，训练过的Elman神经网络能够较好地识别相关函数的特征，分辨不同质量的核材料，平均识别率达到85%，综合平均误差为0.04，且具有较高的鲁棒性。
Filament-wound fibre-reinforced polymer (FRP) tubes are an emerging FRP product employed in various FRP-concrete composite structures, such as concrete-filled FRP tubes (CFFTs). Due to the fibre orientations in the tube wall, the filament-wound FRP tube exhibits biaxial behaviour under simultaneous axial compression and hoop expansion, causing relaxation of the confining stress. Therefore, the conventional hoop tension test may result in overestimation of the confining stiffness. In this paper, the biaxial behaviour of FRP tubes is theoretically investigated using classical laminate theory in conjunction with an analysis-oriented model for FRP-confined concrete. The geometrical meaning of the biaxial tube behaviour is interpreted intuitively using the 3D geometrical approach previously proposed by the authors. For the convenience of analysis and design, this paper proposes a simplified approach to rectify the confining stiffness that considers both elastic and nonlinear biaxial effects. The predicted results show good agreement with the collected test data.
No abstract is provided for this article.
采用先进的CTAB法提取中科一号灵芝菌株的基因组DNA,经过LSD序列的扩增,引物设计,PCR扩增,琼脂糖凝胶电泳检测后用试剂盒回收,转化大肠杆菌感受态细胞,获得正确的转化子后,测序,获得新的灵芝rDNA序列.
ABSTRACT: With the development of new structural materials including FRP (fiber reinforced polymer), glass, stainless steel, the performance of structures have a great change from the steel and the steel reinforced concrete structures. The conventional ductility index that describes the inelastic deformation capacity for the traditional materials cannot longer suit the structures with new materials. A new term, "deformability", has been proposed to extend the concept of the ductility. In this paper, more than ten existing definitions of performance indices for the flexural members are reviewed. A new concept that is design-aimed state is defined relative to ultimate failure state after carrying out analysis based on the comparison in term of concepts and methodologies of the reviewed indices. A new approach to achieve the uniform performance indices and to determine the design-aimed state is proposed also. A set of uniform performance indices, including the deformability index D, the strength index S, the deformation energy index Y and the overall performance index F are presented. The moment-curvature curve of five type of flexural members, including steel beam, steel-reinforced concrete beam, prestressed concrete beam, FRP bars reinforced concrete beam and all-FRP beam, are analyzed using the suggested indices. F-factor is suggested to determine the design-aimed point for all flexural members.
Fatigue failure is brittle and sudden and is one of the main problems with steel members and connections. Carbon fiber reinforced polymer (CFRP) sheets and laminates have been shown to be effective and practical for strengthening steel under fatigue loading regardless of the existence of initial cracks. Many studies have examined the fatigue behaviors of CFRP strengthened steel, but fatigue design guides or available programs for designers and engineers are limited. Thus, based on existing design codes and guidance for pure steel under fatigue loading (e.g., Design Guide for Circular and Rectangular Hollow Section Welded Joints under Fatigue Loading and Recommendations for Fatigue Design of Welded Joints and Components), this paper proposes fatigue design guides and programs for CFRP strengthened steel structures. First, for steel without initial fatigue cracks, Classification method is adopted along with a related calculation method for obtaining the reduced stress range of steel after strengthening. Then, a classification table for hybrid CFRP-steel members is given to illustrate where to glue CFRP sheets or laminates and the correct fiber orientation. Second, for steel with initial fatigue cracks, fracture mechanics are adopted to obtain the reduced stress range. This paper considers debonding at the crack tip using the finite element method (FEM) and introduces a coefficient d to enlarge the range of the stress intensity factor (SIF). Then, a program called “EasyFatigueforFSS” (Easy Fatigue design for FRP Strengthened Steel) is developed to calculate the available life or allowable stress. Finally, typical design examples are given for reference.
No abstract is provided for this article.
Lunar habitat construction is a critical engineering requirement in lunar exploration missions, characterized by unique structural and material challenges distinct from Earth. To meet the demands of in situ large-scale construction in extreme lunar environments, a general mode of “Prefabricated core module & Inflatable structure & In situ materials structure” is adopted. This work analyzed the structural internal forces and foundation bearing capacity for lunar habitats, highlighting the significance of structural tensile performance and the foundation's allowable bearing capacity. A construction scheme based on regolith bags is proposed, encompassing architectural and structural design, and long-term planning. Multiscale experimental investigations conducted on “material, component, structure, and construction” levels confirm the excellent properties of regolith bag. Aramid fabric and CUG lunar regolith simulant were chosen for material and component testing, focusing on evaluating the regolith bag's performance under tension and compression. Successful construction demonstrations of a regolith bag arch structure and a regolith bag – airbag structural unit validate the feasibility of this construction scheme. Conclusively, the proposed lunar habitat construction scheme based on regolith bag technology provides a viable and efficient method for in situ lunar construction.
Buckling limits the slenderness of steel columns in applications. This highly efficient technology, using prestressed (PS) carbon fiber reinforced polymer (CFRP) strips to reinforce steel columns against overall buckling, can be applied in new structures or to strengthen existing structures, and is easy to construct. The buckling behavior of PS CFRP-reinforced steel columns is studied with axial and eccentric compression tests. Axial compression tests are conducted on 8 specimens with three different slenderness values (105, 140, and 200); eccentric compression tests are conducted on PS specimens of slenderness 105 with four different eccentric ratios (0, 1, 2, and 3). The buckling capacity and failure modes are obtained. The obvious reinforcing efficiency is achieved by PS CFRP; the buckling capacity of PS specimens can be increased by 19%–150%. The whole loading procedure is analyzed in detail to further explain the mechanism of PS CFRP reinforcing. Four possible critical states are determined, whose order depends on the reinforcing conditions and influences the cause of buckling, which is either material yielding or slacking of the concave side CFRP. Finally, a simplified model of reinforcing efficiency is preliminarily built based on the test results.
In this work, pullwinding technique is adopted to realize the hybrid roving architecture in pultruded GFRP composites so as to improve their transverse properties as well as the flexural performance of GFRP beams. First, small-scale material characterization tests and large-scale four-point bending tests were conducted to evaluate the mechanical performance of pullwound composites and the flexural behavior of pullwound box-beams. Second, analytical study was performed to calculate the strength and modulus of laminated plates with hybrid roving architectures. Then, finite element modeling was conducted to assess the strength and stability limit states of pullwound beams. The hybrid roving architecture could effectively reduce the material orthotropy, thus improving the transverse properties of GFRP composites as well as the flexural performance of GFRP beams. In the end, a design procedure is proposed to facilitate the design of roving architecture of pullwound composites to achieve the desired mechanical properties.
Fiber-reinforced polymer (FRP) composites have been widely used in civil engineering for either strengthening existing deteriorated reinforced concrete (RC) structures or constructing new structures. Recently, a new category of FRP composites with a large rupture strain (i.e., referred to as “LRS FRP” in this article) has become increasingly popular. In contrast with conventional FRP composites, LRS FRP composites possess a larger elongation and a lower modulus of elasticity. Since the ultimate state of structures with FRP strengthening generally depends on fracture of the FRP, it is expected that an increase in FRP rupture strain leads to a better performance of structures and LRS FRP composites are particularly suitable for enhancing ductility of structures. This paper presents a state-of-the-art review on the basic characteristics of LRS FRP composites and structural usage of LRS FRP composites (including concrete confined with LRS FRP composites), with further research opportunities associated with LRS FRP composites in structural engineering applications being identified.
This paper presents a passive EPC Gen-2 UHF RFID tag chip with a dual-resolution temperature sensor. The chip tag integrates a temperature sensor,an RF/analog front-end circuit,an NVM memory and a digital baseband in a standard CMOS process.The sensor with a low power sigma-delta(ΣΔ) ADC is designed to operate in low and high resolution modes.It can not only achieve the target accuracy but also reduce the power consumption and the sensing time.A CMOS-only RF rectifier and a single-poly non-volatile memory(NVM) are designed to realize a low cost tag chip.The 192-bit-N VM tag chip with an area of 1 mm~2 is implemented in a 0.18-μm standard CMOS process.The sensitivity of the tag is -10.7 dBm/-8.4 dBm when the sensor is disabled/enabled.It achieves a maximum reading/sensing distance of 4 m/3.1 m at 2 W EIRP.The inaccuracy of the sensor is -0.6℃/0.5℃(-1.0℃/1.2℃) in the operating range from 5 to 15℃in high resolution mode(-30 to 50℃in low resolution mode).The resolution of the sensor achieves 0.02℃(0.18℃) in high(low) resolution mode.
