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In the development of low power impregnated cathode, to decrease heater power the Taguchi method has been used. The newly developed low power impregnated cathode can he applied to a new electron gun-we call this technology "L-SAGIC"-enabling the CRT's to achieve good performance and high resolution and brightness.
電磁波レーダを用いたコンクリート構造物内部のひび割れ領域および鉄筋腐食領域の可視化に関する実験的研究を行った．まず，鉄筋かぶり（30，60mm）と腐食率を実験変数として電食実験により局所的な領域に腐食を生じさせた供試体を作製し，内部のひび割れ幅・分布情報および鉄筋の腐食率分布を評価した．この供試体を対象として電磁波レーダより得られる電磁波波形の健全供試体との違いを考慮した指標を自己組織化マップ（SOM）に適用し，内部ひび割れ・腐食領域の可視化を試みた．その結果，1段階のSOM適用により，鉄筋の腐食領域を検出できることを確認した．さらに，2段階のSOM適用による評価を試みたところ，内部ひび割れの存在を定量的かつ明瞭に検出できることを確認し，その適用範囲は内部ひび割れ幅0.1～0.4mm，腐食率4%以上であった．
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1. We have examined changes in caffeine and trimethadione (TMO) metabolism in vivo, agents which are used as probe drugs. In this study the total body clearance (Cl) of caffeine and TMO was low 1 week after birth (week 1), increased rapidly from week 3, peaked and then decreased gradually until reaching the level for the mature, adult dog. The elimination half-life (t1/2) of caffeine and TMO was prolonged during week 1; however, it then gradually became shorter. Gradually it became longer and reached the level for the adult dog. The apparent volume of distribution (Vd) of caffeine did not change throughout the study. However, the Vd of TMO was only high during week 1. 2. The in vitro changes in a variety of typical substrates for seven different cytochrome P450 (CYP) isozymes were examined. In this study three different patterns of metabolism can be identified: (1) activity is low immediately after birth, increases, peaks and then decreases to the adult dog level (p-nitroanisole; CYP1A1, caffeine; CYP1A2, benzphetamine; CYP3A/2B(?), aniline; 2E1 and TMO; CYP2C9/2E1/3A4); (2) activity generally increases rapidly soon after birth, continues to increase, peaks and then gradually decreases to the adult level (phenytoin; CYP2C9); and (3) activity is high (about the same level as the adult) immediately after birth, decreases and then gradually increases to the adult level (erythromycin; CYP3A4/5). 3. The results of these in vivo and in vitro studies suggest that changes in enzyme activity are due to differences in P450 isoenzymes during development.
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ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure of coformycin, an unusual nucleoside of microbial originHikaru Nakamura, Gunji Koyama, Yoichi Iitaka, Masaji Ohno, Naomasa Yagisawa, Shinichi Kondo, Kenji Maeda, and Hamao UmezawaCite this: J. Am. Chem. Soc. 1974, 96, 13, 4327–4328Publication Date (Print):June 1, 1974Publication History Published online1 May 2002Published inissue 1 June 1974https://pubs.acs.org/doi/10.1021/ja00820a049https://doi.org/10.1021/ja00820a049research-articleACS PublicationsRequest reuse permissionsArticle Views316Altmetric-Citations89LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
For local government administrators, it is a key task to make efficient counter-plans for earthquakes by forecasting possible earthquake damage. To support them, this paper proposes integration of analysis and visualization for responses of whole structures located in a city. An integrated earthquake simulator is used to this purpose, since the simulator is aimed to combine various simulation programs to it and to visualize calculated structure responses. Integration uses a wrapper called mediator which is automatically made by analyzing a source code of the simulation program. The possibility of such integration is discussed by developing a prototype of artificial intelligence that makes mediators for a given simulation program.
