Chalcones were synthesized by the reaction of acetyl ferrocene and corresponding aldehhyde under microwave irradiation. Results obtained from spectroscopic (FT-IR, 1 H NMR, 13 C NMR, EI-MS) and elemental analysis of synthesized compounds was in agreement with their chemical structures. UV-visible and fluorescence spectroscopy measurements provided that compound 1 and 2 are good absorbent and fluorescent. Fluorescence polarity study demonstrated that these compounds were sensitive to the polarity of the microenvironment provided by different solvents. In addition, spectroscopic and physicochemical parameters, including electronic absorption, extenction coefficient, Stokes shift, oscillator strength and transition dipole moment, were investigated in order to explore the analytical potential of synthesized compounds. The antibacterial activity of the compound 1 and 2 were first studied in vitro by the disk diffusion assay against two Gram-positive and two Gram-negative bacteria. The minimum inhibitory concentration was then determined with the reference of standard drug chloramphenicol.
The electrochemical properties of 4-[(anthracen -9-ylmethylene)-amino]-1, 5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one have been carried out using cyclic voltammetry and convolution - deconvolution voltammetry combined with digital simulation technique at a platinum electrode in 0.1 mol/L tetraethyl ammonium chloride (TEACl) in solvent acetonitrile (CH3CN). In switching the potential to positive scan, the compound was oxidized by loss of one electron forming radical cataion followed by fast chemical step and the radical cation loss another two electrons producing trication which followed by chemical reaction (ECEEC). The investigated compound was reduced via consumption of two consecutive electrons to form radical anion followed by fast chemical step and the radical anion gain another electron to form dianion followed by chemical step (ECEC mechanism). The electrode reaction pathway and the chemical and electrochemical parameters of the investigated compound were determined using cyclic voltammetry, convolutive voltammetry and chronoamperometry. The Electrochemical data such as a, ks, Eo , D, and kc of the investigated pyrazole derivative were evaluated expeimentally and verified via digital simulation technique Electrochemical behaviour of the pyrazole compound under consideration was presented and discussed.
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
In the title co-crystal, C(6)H(6)N(2)O(2.)C(10)H(12)O(4), the two components are held together by an N-H⋯O(aldehyde) hydrogen bond. Adjacent co-crystals are linked by weaker N-H⋯O(nitro) hydrogen bonds, forming a linear chain. The two aromatic rings of the components are aligned at 75.2 (1)°. The crystal studied was a non-merohedral twin with a 24% minor component.
1,3-Diethyl-2-thio-barbituric acid reacts with 2-anisaldehyde to form the Michael addition product 2-anisylbis(1,3-diethyl-2-thio-barbitur-5-yl)methanate, which crystallizes as the title pyridin-ium salt, C(5)H(6)N(+)·C(24)H(29)N(4)O(5)S(2) (-), when it reacts with the pyridine used to catalyse the reaction. There are two independent ion pairs in the crystal structure. The anion features a methine C atom connected to three six-membered rings; one of the rings carries a hydr-oxy group, which engages in hydrogen bonding with the carbonyl group belonging to another ring. The monoclinic unit cell emulates an ortho-rhom-bic unit cell, and is a twin with a minor twin component of 35%.
In the title mol-ecule, C(23)H(16)N(2)O(2), the two exocyclic C=C bonds bearing the tolyl groups have an E configuration and the beznene rings are oriented at 22.1 (1) and 24.8 (1)° with respect to the mean plane of the atoms of the furan ring.
