White matter microstructure abnormalities in pediatric migraine patients
Article 2015 en
Authors
RM
Roberta Messina
MR
Maria A. Rocca
BC
Bruno Colombo
Abstract
1 min read
Pediatric migraine patients harbor diffuse brain WM microstructural abnormalities. High FA and low MD, AD and RD in these patients might be explained by repeated neuronal activation, which may lead to cell swelling and stimulate activity-dependent myelin-modulation, or by increased fiber and dendritic densities. Both these mechanisms might reflect a hyperexcitability of the brain in migraineurs.
Roberta Messina, Maria A. Rocca, Stefania Bianchi Marzoli, Melissa Petrolini, Iacopo Milesi, Fatima Darvizeh, Francesco Bandello, Gıancarlo Comı, Andrea Falini, Massimo Filippi
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