During electrospinning process, charged web jets solidify with solvent evaporation and form two-dimensional (2D) web-like nanofibers on the collecting plate. In this paper, Poly [(lactic acid)-co-(glycolic acid)] (PLGA) solutions are used to produce different 2D web-like nanofibers, which can mimic the physical features of natural extracellular matrix (ECM) at the nanoscale and improve fibroblast growth. According to mass conservation, the possible mechanisms for the web formation are investigated.
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