Use of the traditional Chinese medicine “compound healthy ear agent” to protect against age-related hearing loss in mice: A proteomics study

Weijun Xuan; Liyi Huang; Yi Xuan; Sizhong Chen; Tang Junbo; Yulong Wei; Xu Pan; Michael R Hamblin

doi:10.1016/j.heliyon.2024.e26914

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Use of the traditional Chinese medicine “compound healthy ear agent” to protect against age-related hearing loss in mice: A proteomics study

Article 2024 en

Abstract

1 min read

The TCM CHEA played a protective role against AHL in mice by regulating the expression of specific proteins and genes in cochlear hair cells and spiral ganglion neurons. Besides the pathways expected to be involved (antioxidant and anti-apoptosis), proteins related to immune response is a new finding of the present study.

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International Journal of Molecular Medicine

Use of the traditional Chinese medicine “compound healthy ear agent” to protect against age-related hearing loss in mice: A proteomics study

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Related publications

Use of the Traditional Chinese Medicine 'Compound Healthy Ear Agent' to Protect Against Age-Related Hearing Loss in Mice: A Proteomics Study

A traditional Chinese medicine compound (Jian Er) for presbycusis in a mouse model: Reduction of apoptosis and protection of cochlear sensorineural cells and hearing.

Parallel mechanisms suppress cochlear bone remodeling to protect hearing

Compound Dihuang Granule Inhibits Nigrostriatal Pathway Apoptosis in Parkinson’s Disease by Suppressing the JNK/AP-1 Pathway

Deletion of the kinase domain from death-associated protein kinase enhances spatial memory in mice