Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation

Peter Carmeliet; Lieve Moons; Roger Lijnen; Myriam Baes; Vincent Lemaı̂tre; Peter G. Tipping; Angela F. Drew; Yves Eeckhout; Steve D. Shapiro; Florea Lupu; Désiré Collen

doi:10.1038/ng1297-439

Related publications

Article1997

77 Urokinase-generated plasmin induces athero-sclerotic aneurysm formation via activation of matrix metalloproteinases

Peter Carmeliet, Peter Carmeliet, Lieve Moons, Lieve Moons, Roger Lijnen, Roger Lijnen, James T. B. Crawley, James T. B. Crawley, V. Lemaı̂tre, V. Lemaı̂tre, Peter G. Tipping, Peter G. Tipping, Alexander C. Drew, Alexander C. Drew, Yves Eeckhout, Yves Eeckhout, Sarah Shapiro, Sarah Shapiro, Florea Lupu, Florea Lupu, D Collen, D Collen

Article2004

485 Inhibition of urokinase and matrix metalloproteinases prevents left ventricular hypertrophy and cardiac failure during hypertension

Stéphane Heymans, Frans Van de Werf, Lieve Moons, Peter Carmeliet

Article2006

Inhibition of Urokinase-Type Plasminogen Activator or Matrix Metalloproteinases Prevents Cardiac Injury and Dysfunction During Viral Myocarditis

Stéphane Heymans, Matthias Pauschinger, Armando De Palma, Angela Kallwellis-Opara, Susanne Rutschow, Melissa Swinnen, Davy Vanhoutte, Fangye Gao, Raimund Torpai, Andrew H. Baker, Elisabeth Padalko, Johan Neyts, Heinz‐Peter Schultheiß, Frans Van de Werf, Peter Carmeliet, Yigal M. Pinto

Article1997

Lack of aneurysm formation in atherosclerotic aorta from urokinase deficient mice

Peter Carmeliet, Lieve Moons, Alexander C. Drew, Peter G. Tipping, Florea Lupu, Roger Lijnen, Désiré Collen

Article1998

Receptor-independent Role of Urokinase-Type Plasminogen Activator in Pericellular Plasmin and Matrix Metalloproteinase Proteolysis during Vascular Wound Healing in Mice

Peter Carmeliet, Lieve Moons, Mieke Dewerchin, Steven Rosenberg, Jean‐Marc Herbert, Florea Lupu, Désiré Collen