Unannotated small RNA clusters associated with circulating extracellular vesicles detect early stage liver cancer — Johann von Felden (2021) | RDL Network
Unannotated small RNA clusters associated with circulating extracellular vesicles detect early stage liver cancer
Gut 71(10): 2069-2080
Article 2021 English
Authors
JF
Johann von Felden
TG
Teresa García‐Lezana
ND
Navneet Dogra
Abstract
1 min read
Surveillance tools for early cancer detection are suboptimal, including hepatocellular carcinoma (HCC), and biomarkers are urgently needed. Extracellular vesicles (EVs) have gained increasing scientific interest due to their involvement in tumour initiation and metastasis; however, most extracellular RNA (exRNA) blood-based biomarker studies are limited to annotated genomic regions.
Johann von Felden, Teresa Garcia-Lezana, Navneet Dogra, Edgar Gonzalez‐Kozlova, Mehmet Eren Ahsen, Amanda J. Craig, Stacey M. Gifford, Benjamin H. Wunsch, Joshua T. Smith, Sung‐Cheol Kim, Jennifer E. L. Diaz, Xintong Chen, Ismaïl Labgaa, Philipp K. Haber, Reena Olsen, Dan Han, Paula Restrepo, Delia D’Avola, Gabriela Hernandez‐Meza, Kimaada Allette, Robert Sebra, Behnam Saberi, Parissa Tabrizian, Amon Asgharpour, Douglas T. Dieterich, Josep M. Llovet, Carlos Cordon‐Cardo, Ash Tewari, Myron Schwartz, Gustavo Stolovitzky, Bojan Losic, Augusto Villanueva
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