Type D SRV‐2 virus‐specific CD8<sup>+</sup> and CD4<sup>‐</sup> CD8<sup>‐</sup> T cells that regulate virus‐induced T cell proliferation in Celebes macaques — Arthur Malley (1993) | RDL Network
Type D SRV‐2 virus‐specific CD8<sup>+</sup> and CD4<sup>‐</sup> CD8<sup>‐</sup> T cells that regulate virus‐induced T cell proliferation in Celebes macaques
Article 1993 en
Authors
AM
Arthur Malley
NP
N. Pangares
SM
Stella Mayo
Abstract
1 min read
These studies defined SRV-2 envelope peptides 96-102, 127-152, and 233-249 as T cell epitopes that induce significant T cell proliferation. Peripheral blood lymphocytes of Celebes macaques (Macaca nigra) exposed to SRV-2 and currently virus- antibody+, cultured with SRV-2 virus show strongly suppressed T cell responses and have two immunoregulatory T cell populations.
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