C1q nephropathy is a distinct clinicopathologic entity, characterized by mesangial immunoglobulin and complement deposits, predominantly C1q, with no evidence for systemic lupus erythematosus. Clinically it may present as nephrotic syndrome and non-nephrotic proteinuria per se or associated with microscopic hematuria, gross hematuria, hypertension, or renal insufficiency. So far there is only one report about a familial case of C1q nephropathy (in two sisters). We present two cases of familial C1q nephropathy with nephrotic syndrome which was steroid resistant, but partially remitted with cyclosporine.
Jin‐Soon Suh, Kyung Mi Jang, Hyesun Hyun, Myung Hyun Cho, Joo Hoon Lee, Young Seo Park, Jae Hyuk Oh, Ji Hong Kim, Kee Hwan Yoo, Woo Yeong Chung, Seong Heon Kim, Kim Kee-Hyuck, Dae Yeol Lee, Jung Won Lee, Min Hyun Cho, Hyewon Park, Ja Wook Koo, Kyoung Hee Han, Eun Mi Yang, Keum Hwa Lee, Jae Il Shin, Heeyeon Cho, Kyo Soon Kim, ,
Federica Castelletti, Roberta Donadelli, Federica Banterla, Friedhelm Hildebrandt, Peter F. Zipfel, Elena Bresin, Edgar A. Otto, Christine Skerka, Alessandra Renieri, Marta Todeschini, Jessica Caprioli, Rosa Caruso, Rosangela Artuso, Giuseppe Remuzzi, Marina Noris
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