Tumor vessel normalization by the autophagy blocker chloroquine: role of endothelial Notch signaling

Hannelore Maes; Anna Kuchnio; Aleksandar Perić; Stijn Moens; Kris Nys; Katrien De Bock; Annelies Quaegebeur; Sandra Schoors; Μαρία Γεωργιάδου; Jasper Wouters; Bart Ghesquière; Stefan Vinckier; Hugo Vankelecom; Marjan Garmyn; Mieke Dewerchin; Wim Annaert; Patrizia Agostinis; Peter Carmeliet

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The autophagy-blocker chloroquine promotes tumor vessel normalization by increasing Notch-signaling

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Tumor Vessel Normalization by Chloroquine Independent of Autophagy

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The autophagy blocker chloroquine normalizes the tumor vasculature

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Chloroquine anticancer activity is mediated by autophagy-independent effects on the tumor vasculature

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