Transgenerational increases in DNA methylation in Arabidopsis plants defective in active DNA demethylation

Kai Tang; Xiaohong Zhu; Shaojun Xie; Zhaobo Lang; Jian Kang Zhu

doi:10.1073/pnas.2320468121

Abstract

1 min read

Spontaneous gain or loss of DNA methylation occurs in plant and animal genomes, and DNA methylation changes can lead to meiotically stable epialleles that generate heritable phenotypic diversity. However, it is unclear whether transgenerational epigenetic stability may be regulated by any cellular factors. Here, we examined spontaneously occurring variations in DNA methylation in wild-type and

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