Transfusion requirements in septic shock patients: a randomized controlled trial

Perioperative red blood cell transfusion is commonly used to address anemia, an independent risk factor for morbidity and mortality in critically ill patients [1]; however, evidence regarding optimal blood transfusion practice in septic shock is lacking. The aim of this study was to define which is the best transfusion strategy in septic shock patients regarding 28-day mortality and clinical outcomes: restrictive or liberal.