Tracking Cortical Changes Throughout Cognitive Decline in Parkinson's Disease

Massimo Filippi; Elisa Canu; Giulia Donzuso; Tanja Stojković; Silvia Basaia; Iva Stanković; Aleksandra Tomić; Vladana Marković; Igor Petrović; Elka Stefanova; Vladimir Kostić; Federica Agosta

doi:10.1002/mds.28228

Abstract

1 min read

Cortical thinning progression is more prominent in the initial stages of PD cognitive decline. The involvement of frontotemporoparietal regions, the hippocampus, and the thalamus is associated with conversion to a more severe stage of cognitive impairment. In PD, gray matter alterations of critical brain regions may be an MRI signature for the identification of patients at risk of developing dementia. © 2020 International Parkinson and Movement Disorder Society.

Related publications

Article2019

Tracking Cortical Changes Throughout Cognitive Decline in Parkinson’s Disease: A Longitudinal MRI Study (P5.8-016)

Elisa Canu, Federica Agosta, Tanya Stojkovic, Silvia Basaia, Iva Stanković, Vladana Marković, Igor Petrović, Elka Stefanova, Vladimir Kostić, Massimo Filippi

Article2016

Cortical Thinning Associated with Mild Cognitive Impairment in Parkinson's Disease (P4.103)

Sebastiano Galantucci, Federica Agosta, Igor Petrović, Elka Stefanova, Elisa Canu, Massimiliano Copetti, Vladimir Kostić, Massimo Filippi

Article2015

White Matter Microstructural Damage and Cognitive Impairment in Parkinson’s Disease (S40.005)

Sebastiano Galantucci, Federica Agosta, Delia Gagliardi, Francesca Caso, Iva Stanković, Igor Petrović, Tanya Stojkovic, Vladimir Kostić, Massimo Filippi

Article2020

Progressive brain atrophy and clinical evolution in Parkinson’s disease

Massimo Filippi, Elisabetta Sarasso, Noemi Piramide, Tanja Stojković, Iva Stanković, Silvia Basaia, Andrea Fontana, Aleksandra Tomić, Vladana Marković, Elka Stefanova, Vladimir Kostić, Federica Agosta

Article2017

White matter microstructural damage as predictor of cognitive decline in Parkinson’s disease (P4.028)

Sebastiano Galantucci, Federica Agosta, Tanja Stojković, Igor Petrović, Elisa Canu, Elka Stefanova, Massimiliano Copetti, Vladimir Kostić, Massimo Filippi