Total NT-proBNP, a novel biomarker related to recurrent atrial fibrillation

Lidia Staszewsky; Jennifer Meessen; Deborah Novelli; Ursula‐Henrike Wienhues‐Thelen; M Disertori; Aldo Maggioni; Serge Masson; Gianni Tognoni; Maria Grazia Franzosi; Donata Lucci; Roberto Latini

doi:10.1186/s12872-021-02358-y

Abstract

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The association of total NT-proBNP with the risk of AF first recurrence was similar to that of NT-proBNP, suggesting no influence of glycosylation. Analogous results were obtained for the risk of first hospitalization for CV reasons. Natriuretic peptides, Ang2 and BMP10 were associated with ongoing AF. Findings from the last two biomarkers point to a pathogenic role of cardiac extracellular matrix and cardiomyocyte growth in the myocardium of the right atrium and ventricle.

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