Tissue Engineering: Engineering Silk Fibroin‐Based Nerve Conduit with Neurotrophic Factors for Proximal Protection after Peripheral Nerve Injury (Adv. Healthcare Mater. 2/2021)

The incorporation and delivery of neurotrophic factors that stimulate nerve repair in previously developed tunable enzymatically crosslinked silk fibroin-based conduits are presented. In article number 2000753 by Joaquim M. Oliveira and co-workers, glial cell line-derived neurotrophic factor (GDNF), acting upon motor and sensory neurons, also instigating angiogenesis, uses these conduits as a platform for its controlled delivery, enhancing motor and sensory regeneration both in vivo and in vitro.